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DeCS
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Descritor Inglês:
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Anaphase-Promoting Complex-Cyclosome
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Descritor Espanhol:
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Ciclosoma-Complejo Promotor de la Anafase
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Descritor Português:
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Ciclossomo-Complexo Promotor de Anáfase
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Sinônimos Inglês:
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Anaphase Promoting Complex
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Categoria:
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D08.811.464.938.750.092
D12.776.167.024
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Definição Inglês:
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An E3 ubiquitin ligase primarily involved in regulation of the metaphase-to-anaphase transition during MITOSIS through ubiquitination of specific CELL CYCLE PROTEINS. Enzyme activity is tightly regulated through subunits and cofactors, which modulate activation, inhibition, and substrate specificity. The anaphase-promoting complex, or APC-C, is also involved in tissue differentiation in the PLACENTA, CRYSTALLINE LENS, and SKELETAL MUSCLE, and in regulation of postmitotic NEURONAL PLASTICITY and excitability. |
Nota Histórica Inglês:
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2014
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Qualificadores Permitidos Inglês:
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Número do Registro:
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55272
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Identificador Único:
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D064173
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Ocorrência na BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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